Development, Standardisation and Accelerated Stability Studies of a Polyherbal Formulation

Rheumatoid Arthritis is a chronic, inflammatory, systemic autoimmune disease characterized by pain, swelling and stiffness. Allopathic medications have been prescribed to alleviate symptoms of this disease that results into associated side effects like gastrointestinal disorders, cardiovascular risks, immunodeficiency, hepatotoxicity and renal toxicity. The use of herbal medicine is becoming popular due to toxicity and side effects of allopathic medicine. Several herbs have been used traditionally for relieving the symptoms of rheumatoid arthritis. The antiarthritic polyherbal formulation composed of four medicinal plants namely Imbatiens balsamina, Capparis decidua, Dioscorea alata, Onosma bracteatum. The aim of the study was to develop a polyherbal formulation (polyherbal capsules) to treat Rheumatoid arthritis to set up its quality control standards by evaluating its physicochemical, phytochemical and formulation parameters. The optimized batch was subjected to accelerated stability studies to ascertain the stability of the formulation.